Neuron-specific Sumo1–3 knockdown in mice impairs episodic and fear memories
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چکیده
منابع مشابه
Neuron-specific Sumo1-3 knockdown in mice impairs episodic and fear memories.
BACKGROUND Growing evidence suggests that small ubiquitin-like modifier (SUMO) conjugation plays a key role in brain plasticity by modulating activity-dependent synaptic transmission. However, these observations are based largely on cell culture experiments. We hypothesized that episodic and fear memories would be affected by silencing SUMO1-3 expression. METHODS To investigate the role of SU...
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ژورنال
عنوان ژورنال: Journal of Psychiatry & Neuroscience
سال: 2014
ISSN: 1180-4882
DOI: 10.1503/jpn.130148